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Clinical Study

Using a new ADHD Remote Technology (‘ART’) system, developed at King’s College London (Kuntsi, Dobson et al.), the ART-CARMA project aims to obtain real-world data from the daily life of 300 adults with ADHD on the extent to which ADHD medication treatment and physical activity, individually and jointly, may influence cardiometabolic risks. A second main aim of the project is to obtain detailed real-world data from the patients’ daily life on adherence to pharmacological treatment and its predictors and correlates, over a remote monitoring period of 12 months that starts from pre-treatment initiation. The remote assessments consist of both active (smartphone active app) and passive (smartphone passive app and a wearable device) monitoring. The wearable device is the new EmbracePlus developed by the SME partner Empatica. The ART system is linked to the RADAR mobile-health platform.

ART-CARMA involves two data collection sites: 150 participants will be recruited in London by the King’s College London (KCL) team and another 150 participants in Barcelona by the Vall d’Hebron Research Institute (VHIR) team. The KCL team is led by Professor Jonna Kuntsi (Principal Investigator) and Professor Richard Dobson (CoInvestigator). Other KCL team members include Hayley Denyer and Dr Amos Folarin, and collaborating Consultant Psychiatrists Dr Susie Whitwell (South London and Maudsley, SLaM, adult ADHD clinic) and Dr Ulrich MullerSedgwick (Barnet, Enfield and Haringey Mental Health NHS Trust adult ADHD clinic). The VHIR team is led by Professor J. Antoni Ramos-Quiroga and among his collaborators are Dr Marta Ribasés as Coordinator of the Psychiatric Genetics Unit, the Psychiatrists Dr Vanesa Richarte and Dr Christian Fadeuilhe, the Psychologist Dr Montserrat Corrales, the Cardiologist Dr Ignacio Ferreira, the Endocrinologist Dr Andreea Ciudin, the Psychologist/researcher Carolina Ramos and Raquel Ibarz as Project Manager.